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MEDICATIONS




TOPAMAX (Topiramate)



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Topamax is an antiepileptic drug used for treating partial and generalized tonic-clonic seizures. Topamax is also approved for the treatment of seizures associated with the Lennox-Gastaut syndrome. It is approved for use in combination with other antiepileptic drugs.

Dosage forms



Topamax is available in tablet form (25 mg, 100 mg, 200 mg). Topamax is also available in 15 mg and 25 mg sprinkle capsules.

What side effects can be caused by Topamax?



Just like other drugs, Topamax can cause side effects. Also, every patient is different. If you experience any bothersome side effects, report them to your doctor. (There is a risk of serious side effects, including death, with all medications that are used to treat seizures; however, the risk is very small). This list is not meant to be exhaustive. Please refer to the package insert for more details about Topamax.

Some of the common side effects of Topamax include:

  1. Difficulty with concentration/attention
  2. Lack of appetite
  3. Weight loss
  4. Cognitive difficulties
  5. Decreased sweating (oligohidrosis)

Rare, but serious side effects:

  1. Kidney stones/Salivary stones
  2. Liver problems
  3. Acute angle-closure glaucoma
  4. Women who plan to have children should consult with their doctor about the possible effects on the fetus.

How should I take Topamax?



It is important that you take the total dose of Topamax as prescribed by your doctor. Topamax is normally taken two times a day. A convenient dosing would be at breakfast and at bedtime. Do not stop this medication without the advice of your doctor; doing so may result in an increase in seizures.

Does Topamax interact with other medications?



Tegretol/Carbatrol (carbamazepine) and Dilantin (phenytoin) may affect topiramate levels in the blood stream. Topamax may decrease the efficacy of oral contraceptives.

This list is not meant to be complete. Please ask your doctor about any specific drug-drug interactions, especially when starting a new prescribed or over-the-counter drug.

Can I take Topamax with food or other medications?



Yes, Topamax can be taken with meals and at the same time as other medications.

© 2004 The Neurological Institute of New York • Columbia Comprehensive Epilepsy Center. 710 W 168th St, New York, NY 10032. Phone: 212-305-1742
Department of Neurology | Columbia University Medical Center | Last updated: December 12, 2012 | Comments
 

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