Telephone: 212-305-1742 || Email: epilepsy@neuro.columbia.edu

RESEARCH OPEN TO PARTICIPATION

There are several studies at the Comprehensive Epilepsy Center that are currently enrolling patients. Our current studies with a brief description are listed below. Click on the study for more details.

Subjects may receive compensation for participation. If you are interested in participating or have any questions about research studies, please e-mail Alison Randall or call 212.305.1684.

RESEARCH RESULTS FROM THE COLUMBIA COMPREHENSIVE EPILEPSY CENTER

» Bone Health and Epilepsy
» Implanted Devices for the Treatment of Epilepsy
» New Antiepileptic Drugs and Compounds
» Sleep and Epilepsy

I. CURRENT CLINICAL RESEARCH STUDIES

Carvedilol for Refractory Epilepsy
Purpose: To find out if taking Carvedilol (tradename Coreg) with standard Antiepileptic drugs will improve the frequency of epileptic seizures.

The Family Studies in Epilepsy Program
The Family Studies in Epilepsy Program at Columbia University’s Mailman School of Public Health is a long-term research study focused on finding the genes involved with inherited forms of Idiopathic Generalized Epilepsies[lh6].

Intranasal Clonazepam
Purpose: To find out if intranasal clonazepam is effective in treating frequent seizures

International Rolandic Epilepsy Linkage and NeuroDevelopment (Ireland) Study

Eszopiclone for Insomnia in Epilepsy
Purpose: To find out if using eszopiclone in people with epilepsy and insomnia can improve sleep.

Bone and Hormonal Health in Older Men and Women with Epilepsy
Purpose: To find out about how epilepsy medications affect bone health in people with epilepsy

Genetics of epilepsy
The study is examining the genetic component of certain kinds of epilepsies.

Language Functioning Study
The goal of this study is to assist in preserving language abilities after surgery. Subjects may receive compensation for participation.

Neuroepidemiology of seizures
The study is examining the genetic component of certain kinds of epilepsies.

Pregabalin Insomnia Study
Purpose: To find out if using pregabalin is people with epilepsy and insomnia can improve sleep.

Progesterone Study
Purpose: To find out if using progesterone can help to control seizures in women with epilepsy.

RNS (Responsive Neurostimulator)
In this trial, a device is implanted that can detect seizure onset and potentially stop seizures with a direct stimulus to the affected area. The trial is appropriate only for patients with epilepsy refractory to medication.

Rufinamide
Purpose: A research study to find out if the investigational drug rufinamide can help to control seizure activity.

II. BASIC EPILEPSY RESEARCH