CLINICAL RESEARCH STUDIES
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BONE AND HORMONAL HEALTH IN PEOPLE WITH EPILEPSY
Purpose:
To find out about how epilepsy medications affect bone health in people with epilepsy.
Inclusion criteria:
Men and women age 50-70, at least 5 years post-menopausal if female, diagnosis of epilepsy, not receiving hormone therapy or therapy for osteoporosis, taking one or more of the following medications for epilepsy: Dilantin, Tegretol, Lamictal, Keppra, Neurontin, or Lyrica
OR
Women age 18-48, having regular menstrual periods, diagnosis of epilepsy, on stable antiepileptic drugs for at least 6 months, not receiving treatment for osteoporosis, not pregnant or breastfeeding.
Study participation includes a 24 hour urine collection to be done at home, and one appointment of approximately 3 hours where questionnaires on diet and exercise will be completed, blood will be drawn, a urine sample will be taken, medical and seizure histories will be reviewed, and subjects will have a bone density test (DXA) and CT scan of their wrist and heel (pQCT).
Please contact Robert Pelgrift (212-305-1617; rp2236@columbia.edu).
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